Pneumonocyte; any cell of the walls of the pulmonary alveoli; often restricted to the cells of the alveolar epithelium (squamous alveolar cells and great alveolar cells) and alveolar phagocytes.
See also Epithelial Cell Markers
Alkaline phosphatase
a marker of alveolar type II cell differentiation.
PMID: 2462386
Cytokeratin
cytokeratin synthesis is a marker of type 2 cell differentiation in adult
and maturing fetal lung alveolar cells.
PMID: 2458290
HTI56
an integral apical membrane protein of the human alveolar type I cell. PMID: 10424584
MEP-1
new type I alveolar epithelial cell marker of the rat.
PMID: 8720458
MPA (Maclura
pomifera lectin)
cell-specific marker for alveolar epithelium in fetal rat lung. PMID: 2189457
MPA binding
glycoproteins (MPA-gp330)
has an apparent
molecular weight of 330 kD and is analogous to a similar membrane
glycoprotein found in rat and rabbit type 2 cells.
PMID: 2733026
a candidate for a differentiation marker for alveolar type II cells in
adult rat lung.
Preliminary data suggests that this 185 kd MPA binding glycoprotein
is not found in ATI cells.
PMID: 2916648
P2X7 and GABRP
identified in
this study could be used as potential AEC I and AEC II markers for
studying lung epithelial cell biology and monitoring lung injury.
PMID: 15184050
pro-SPC
a marker specific
for alveolar type II pneumocytes.
PMID: 12761850
RAGE (receptor
for advanced glycation endproducts)
the highly selective differentiation marker of human alveolar epithelial
type I cells.
PMID: 16315007
a marker for
basolateral membranes of well-differentiated ATI cells. ATI cells
require some signal provided by the in vivo environment to express
RAGE.
PMID: 15009093
RTI(40)
an alveolar type
I cell-specific protein, has been shown to be an accurate marker of
alveolar epithelial damage.
PMID: 10712353
a differentiation marker of type I alveolar epithelial cells.
PMID: 9761764
SBA (Soybean agglutinin)
a marker of type I alveolar epithelial cells and alveolar macrophages in
mini pigs.
PMID: 7518176
SPA (surfactant
protein A, SP-A)
alveolar type II cell markers in acinar adenocarcinomas and adenoid cystic
carcinomas arising from segmental bronchi.
PMID: 8386445
SPB (surfactant
protein B, SP-B)
SPB promoter
activity is restricted in the adult to type II alveolar epithelial
cells and bronchial epithelial cells.
PMID: 11238857
SPB gene
transcription is restricted to bronchiolar and alveolar epithelium.
PMID: 7958446
a 79-amino-acid
hydrophobic protein that enhances the surface active properties of
pulmonary surfactant. SPB is expressed in nonciliated bronchiolar
and alveolar type II cells of the respiratory epithelium, and its
expression increases markedly late in gestation.
PMID: 8496176
SPC (surfactant
protein C, SP-C)
a type II
pneumocyte-specific gene,
is a definitive type II alveolar cell marker.
PMID: 12950082,
PMID: 15268776
an alveolar Type
II cell-specific marker.
PMID: 12699910
cell-specific
marker of alveolar type II cells.
PMID: 9070353